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Bipolar Disorder

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Bipolar Disorder definition

Bipolar disorder is a serious mental illness. People who have it go through unusual mood changes. They go from very happy, up,and active to very sad and hopeless, down, and inactive, and then back again. They often have normal moods in between. The up feeling is called mania. The down feeling is depression.

Supplements that help with Bipolar Disorder

  • Ashwagandha for Bipolar Disorder

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Slightly Positive

Although results are preliminary, WSE appears to improve auditory-verbal working memory (digit span backward), a measure of reaction time, and a measure of social cognition in bipolar disorder. Given the paucity of data for improving cognitive capacity in bipolar disorder, WSE offers promise, appears to have a benign side-effects profile, and merits further study.

  • Chromium for Bipolar Disorder

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Slightly Positive

  • Fish Oil for Bipolar Disorder

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Slightly Positive

This study did not find overall evidence of efficacy for adjunctive treatment with EPA 6 g/day in outpatients with bipolar depression or rapid cycling bipolar disorder.
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Slightly Positive

Adjunctive ethyl-EPA is an effective and well-tolerated intervention in bipolar depression.
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Slightly Positive

Omega3 fatty acids were well tolerated and improved the short-term course of illness in this preliminary study of patients with bipolar disorder.
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Slightly Positive

Omega-3 fatty acids lowered T(2) values, consistent with the hypothesis that the fluidity of cell membranes was altered. Further studies are needed to clarify the significance of alterations in brain physiology induced by omega-3 fatty acids, as reflected in T(2) values.
test
Slightly Positive

Despite preclinical studies suggesting that the effect of O3FA might be augmented with pyrimidines, add-on CYT did not substantially improve mood symptoms in BD. In addition, although a power analysis indicated that the sample size would be adequate to see beneficial effects similar to those previously reported, O3FA treatment by itself was not superior to placebo for BD.

  • Uridine for Bipolar Disorder

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Slightly Positive

In this pilot case series, uridine was efficacious and well tolerated by study participants. Rapid onset of action may be a distinguishing feature of uridine. Open-label studies are an initial step in testing a novel intervention, and these findings should be considered preliminary. Uridine should not enter clinical practice as a primary treatment for depressed adolescents with bipolar disorder until randomized placebo-controlled trials have been performed to confirm its efficacy.

Supplements that may help with Bipolar Disorder when combined

No supplements that have a synergystic effect to help reduce the symptoms of this health condition.

What functions are affected by Bipolar Disorder

Mental health

What body systems are affected by Bipolar Disorder


Nervous System
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