Role of melatonin in mucosal gastroprotection against aspirin-induced gastric lesions in humans. – Cost Effective Supplements

Role of melatonin in mucosal gastroprotection against aspirin-induced gastric lesions in humans.

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Link to full study

http://www.ncbi.nlm.nih.gov/pubmed/20443220

Conclusion of this study

Plasma gastrin levels were raised in subjects given melatonin or tryptophan plus ASA, but not in those with ASA alone. We conclude that melatonin and its precursor tryptophan given orally significantly reduce gastric lesions induced by ASA possibly due to (a) direct gastroprotective action of exogenous melatonin or that generated from tryptophan and (b) gastrin released from the gastric mucosa by melatonin or tryptophan.