Brain serotonin and dopamine modulators, perceptual responses and endurance performance during exercise in the heat following creatine supplementation.
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Link to full study
http://www.ncbi.nlm.nih.gov/pubmed/18826587
Conclusion of this study
Although Cr influenced key modulators of brain 5-HT and DA function and reduced various thermophysiological parameters which all may have contributed to the reduced effort perception during exercise in the heat, performance was improved only in the "responders" to Cr supplementation. The present results may also suggest the demanding of the pre-experimental identification of the participants into "responders" and "non-responders" to Cr supplementation before performing the main experimentation. Otherwise, the possibility of the type II error may be enhanced.
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