Significant reductions were found in fine wrinkling, mottled hyperpigmentation, roughness, and laxity after 0.05% tretinoin therapy when compared with controls. In addition, histologic changes of increased epidermal thickness, decreased melanin content, and stratum corneum compaction provide independent evidence supporting clinical improvement. Side effects of erythema, peeling, and stinging were usually mild and well tolerated.

Vitamin A

Health conditions analyzed in this study

Dry skin

1 supplement Slightly Negative Vitamin A

Skin Aging

1 supplement Moderately Positive Vitamin A

Functions related to this study

Skin, hair and nails

1 supplement Moderately Positive Vitamin A

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Body systems related to this study

Integumentary system

1 supplement Vitamin A