Acute inositol does not attenuate m-CPP-induced anxiety, mydriasis and endocrine effects in panic disorder.
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Link to full study
http://www.ncbi.nlm.nih.gov/pubmed/9352475
Conclusion of this study
The authors investigated the effect of a single dose of 20 g inositol on an m-CPP challenge in a double-blind placebo-controlled crossover trial in panic-disorder patients. Seven patients had robust psychological, physiological and endocrine responses to 0.08 mg m-CPP i.v.; inositol had virtually no effect on these responses, although it had some acute effects during the evening before the challenge. A similar trial involving chronic inositol would be of interest.
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