Aqueous extract of Astragali Radix induces human natriuresis through enhancement of renal response to atrial natriuretic peptide.
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http://www.ncbi.nlm.nih.gov/pubmed/18243612
Conclusion of this study
The change in U(Na)V was closely correlated with pANP, U(cGMP)V, and U(cGMP)V/pANP ratio. In addition, the seven volunteers who presented marked natriuresis did not show higher level of plasma Astragaloside IV than the other five volunteers. We first demonstrate that ARE induces a marked natriuresis in healthy men, which is attributed to enhanced renal responses to endogenous ANP. The Astragaloside IV in the ARE is not the active component for natriuresis.
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