Subjects with essential hypertension are more sensitive to the inhibition of 11 beta-HSD by liquorice.
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Link to full study
http://www.ncbi.nlm.nih.gov/pubmed/12574791
Conclusion of this study
The increase in Q was prominent (p<0.0001) and correlated to the rise in BP (p=0.02). The rise in BP was not dependant on age, the change in plasma renin activity or weight. We conclude that patients with essential HT are more sensitive to the inhibition of 11 beta-HSD by liquorice than NT subjects, and that this inhibition causes more clinical symptoms in women than in men.
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Body systems related to this study
Cardiovascular System |
Endocrine System |