Topical nicotinamide compared with clindamycin gel in the treatment of inflammatory acne vulgaris.
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Link to full study
http://www.ncbi.nlm.nih.gov/pubmed/7657446
Conclusion of this study
These data demonstrate that 4% nicotinamide gel is of comparable efficacy to 1% clindamycin gel in the treatment of acne vulgaris. Because topical clindamycin, like other antimicrobials, is associated with emergence of resistant microorganisms, nicotinamide gel is a desirable alternative treatment for acne vulgaris.
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