Krill oil significantly decreases 2-arachidonoylglycerol plasma levels in obese subjects.
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Link to full study
http://www.ncbi.nlm.nih.gov/pubmed/21276269
Conclusion of this study
These data show for the first time in humans that relatively low doses of LCPUFA n-3 as KO can significantly decrease plasma 2-AG levels in obese subjects in relation to decrease of plasma phospholipid n-6/n-3 LCPUFA ratio. This effect is not linked to changes of metabolic syndrome parameters but is most likely due to a decrease of 2-AG biosynthesis caused by the replacement of 2-AG ultimate precursor, arachidonic acid, with n-3 PUFAs, as previously described in obese Zucker rats.
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Nervous System |