Study

A volunteer model for the comparison of laxatives in opioid-related constipation. – Cost Effective Supplements

A volunteer model for the comparison of laxatives in opioid-related constipation.

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http://www.ncbi.nlm.nih.gov/pubmed/8935140


Conclusion of this study

A combination of stimulant and softening laxatives was most likely to maintain normal bowel function at the lowest dose and least adverse effects. The mean final dose of lactulose was excessive for use in ill patients. Senna was associated with significantly more adverse effects than the other laxatives, mainly abdominal pain (P < 0.001). This model of constipation may provide a standardized means of assaying the clinical effectiveness of oral laxatives.


Supplements analyzed in this study

Senna alexandria

Health conditions analyzed in this study

Constipation


Highly Positive
Senna alexandria


Functions related to this study

Digestion


Highly Positive
Senna alexandria


Body systems related to this study


Digestive System
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