Nicotinic acid effects on insulin sensitivity and hepatic lipid metabolism: an in vivo to in vitro study.
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Link to full study
http://www.ncbi.nlm.nih.gov/pubmed/24806747
Conclusion of this study
This effect was associated with an increase in diacylglycerol and a decrease in tri-glyceride contents that occurred in the absence of modification of DGAT2 expression and activity. Eight weeks of Niaspan(®) treatment in dyslipidemic patients with metabolic syndrome induce hepatic insulin resistance. The mechanism could involve an accumulation of diacylglycerol and an alteration of insulin signaling in hepatocytes.
Supplements analyzed in this study
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Health conditions analyzed in this study
No health conditions information for this study.Functions related to this study
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Body systems related to this study
Cardiovascular System |
Digestive System |