Study

Nicotinic acid effects on insulin sensitivity and hepatic lipid metabolism: an in vivo to in vitro study. – Cost Effective Supplements

Nicotinic acid effects on insulin sensitivity and hepatic lipid metabolism: an in vivo to in vitro study.

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http://www.ncbi.nlm.nih.gov/pubmed/24806747


Conclusion of this study

This effect was associated with an increase in diacylglycerol and a decrease in tri-glyceride contents that occurred in the absence of modification of DGAT2 expression and activity. Eight weeks of Niaspan(®) treatment in dyslipidemic patients with metabolic syndrome induce hepatic insulin resistance. The mechanism could involve an accumulation of diacylglycerol and an alteration of insulin signaling in hepatocytes.


Supplements analyzed in this study

Vitamin B3

Health conditions analyzed in this study

No health conditions information for this study.

Functions related to this study

Heart health


Highly Positive
Vitamin B3

Insulin control


Slightly Negative
Vitamin B3


Body systems related to this study


Cardiovascular System

Digestive System
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