This small, preliminary, open study of creatine monohydrate suggests a beneficial effect of creatine augmentation in unipolar depression, but possible precipitation of a manic switch in bipolar depression.

Creatine

Health conditions analyzed in this study

Depression

1 supplement Moderately Positive Creatine

Functions related to this study

Emotional health

1 supplement Moderately Positive Creatine

---

Body systems related to this study

Nervous System

1 supplement Creatine