CMH supplementation increases global DNA methylation statistically significantly. Scores were lower for creatine than for placebo reflecting clinical improvement but not reaching statistical significance. Biochemical variables of methionine-homocysteine remethylation are unaffected. Multicenter studies are urgently warranted to evaluate the long-term effects of CMH supplementation in an optimally homogenous RTT population over a prolonged period.

Creatine

Health conditions analyzed in this study

Functions related to this study

Antioxidant potential

1 supplement Slightly Negative Creatine

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Body systems related to this study

Overall Systems

1 supplement Creatine