Titrated extract of Centella asiatica (TECA) in the treatment of venous insufficiency of the lower limbs.
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Link to full study
http://www.ncbi.nlm.nih.gov/pubmed/3544968
Conclusion of this study
A significant difference (p less than 0.05) in favor of TECA was shown for the symptoms of heaviness in the lower limbs and edema, as well as for the overall evaluation by the patient. The venous distensibility measured by a mercury strain gauge plethysmograph at three occlusion pressures was improved for the TECA groups but aggravated for the placebo group.
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