Study

Licorice extract and its major polyphenol glabridin protect low-density lipoprotein against lipid peroxidation: in vitro and ex vivo studies in humans and in atherosclerotic apolipoprotein E-deficient mice. – Cost Effective Supplements

Licorice extract and its major polyphenol glabridin protect low-density lipoprotein against lipid peroxidation: in vitro and ex vivo studies in humans and in atherosclerotic apolipoprotein E-deficient mice.

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http://www.ncbi.nlm.nih.gov/pubmed/9250104


Conclusion of this study

Dietary supplementation of each E zero mouse with licorice (200 micrograms/d) or pure glabridin (20 micrograms/d) for 6 wk resulted in a substantial reduction in the susceptibility of their LDL to oxidation along with a reduction in the atherosclerotic lesion area. These results could be related to the absorption and binding of glabridin to the LDL particle and subsequent protection of the LDL from oxidation by multiple modes as shown in humans and in E zero mice.


Supplements analyzed in this study

Licorice

Health conditions analyzed in this study

Atherosclerosis


Moderately Positive
Licorice


Functions related to this study

Antioxidant potential


Slightly Positive
Licorice

Heart health


Moderately Positive
Licorice


Body systems related to this study


Cardiovascular System

Overall Systems
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