Pilot controlled trial of D-serine for the treatment of post-traumatic stress disorder.
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Link to full study
http://www.ncbi.nlm.nih.gov/pubmed/19366490
Conclusion of this study
DSR treatment was well tolerated and resulted in significantly (p=0.03) increased DSR serum levels. Compared with placebo administration, DSR treatment resulted in significantly reduced HAMA (p=0.007) and MISS (p=0.001) scores and a trend (p=0.07) towards improved CAPS total scores. These preliminary findings indicate that NMDAR glycine site-based pharmacotherapy may be effective in PTSD and warrant larger-sized clinical trials with optimized DSR dosages.
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