Comparison of the effect of drugs upon some commonly used measures of bowel transit time.
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Link to full study
http://www.ncbi.nlm.nih.gov/pubmed/728318
Conclusion of this study
Gut transit time was assessed by dye and radio-opaque marker methods. 2 It was possible to demonstrate the effect of the anthracenes but not oxyphenisatin on gut transit time. 3 More sophisticated statistical techniques were required to demonstrate the retarding effect of the sympathomimetic amine and its reversal by senna. 4 Statistical analysis shows that assessment of intestinal transit time by dye or pellet methods gives identical information.
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