Comparison of Pycnogenol and Daflon in treating chronic venous insufficiency: a prospective, controlled study.
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Link to full study
http://www.ncbi.nlm.nih.gov/pubmed/16708123
Conclusion of this study
In conclusion, this study confirms the fast clinical efficacy of Pycnogenol in patients with chronic venous insufficiency and venous microangiopathy and its superiority-considering the evaluated parameters-to the combination of diosmin and hesperidin.
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