The safety of oral use of L-glutamine in middle-aged and elderly individuals.
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Link to full study
http://www.ncbi.nlm.nih.gov/pubmed/19765954
Conclusion of this study
Increases in serum urea nitrogen and creatinine and decrease in eGFR are probably due to difficulties by older kidneys in metabolizing the supplemented protein sources. Although not clinically significant, those alterations impose a rigorous control on the evaluation parameters of renal function during oral L-Gln supplementation, with doses of 0.5 g kg(-1) d(-1) in middle-aged and elderly individuals.
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