Efficacy of senna versus lactulose in terminal cancer patients treated with opioids. – Cost Effective Supplements

Efficacy of senna versus lactulose in terminal cancer patients treated with opioids.

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Link to full study

http://www.ncbi.nlm.nih.gov/pubmed/9436336

Conclusion of this study

Laxative efficacy was analyzed through t test and analysis of variance. No difference was found between the laxatives in defecation-free intervals or in days with defecation. The final scores for general health status were similar in both groups. Given that the two treatments have similar efficacy and adverse effects, a recommendation is made for the use of senna because its cost is lower than lactulose.