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Licorice

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What are Licorice's other names?

  • Glycyrrhiza
  • Glycyrrhiza Glabra
  • Glycyrrhiza Uralensis
  • Liquorice
  • Yashtimadhu

What is Licorice's recommended dosage?

  • Recommended daily intake: 150 - 300 mg

What supplements interact with Licorice?

  • Licorice and Milk Thistle

  • Licorice and Valerian


What can Licorice help with?

  • Licorice for Atherosclerosis

  • Licorice for Canker Sores


What is Licorice used for?

  • Licorice for Heart health

  • Licorice for Antioxidant potential

  • Licorice for Overall health

  • Licorice for Digestion

  • Licorice for Joint support

  • Licorice for Testosterone


What are Licorice's effects on the body?

  • Licorice for the Cardiovascular System

  • Licorice for the Digestive System

  • Licorice for the Endocrine System

We suggest that the glycyrrhetinic acid constituent of liquorice increases circulating and thereby, salivary levels of unconjugated deoxycorticosterone and dehydroepiandrosterone by inhibiting their conjugation at source within the adrenal cortex. This effect may contribute to the mineralocorticoid actions of glycyrrhetinic acid and gives substance to claims that liquorice also has androgenic properties.


In the actual study we treated more cases with the same amount of licorice and reproduced our previous data. The mean testosterone values decreased by 26 % after one week of treatment (p < 0.01). There was also a significant increase in 17-OHP and LH concentrations and a slight, but not significant decrease in free testosterone. Licorice treatment, in addition, did not affect the response of testosterone and 17-OHP to stimulation with beta-HCG.


licorice can increase serum PTH and urinary calcium levels from baseline value in healthy women after only 2 months of treatment. The effect of licorice on calcium metabolism is probably influenced by several components of the root, which show aldosterone-like, estrogen-like and antiandrogen activity.


Licorice can reduce serum testosterone probably due to the block of 17-hydroxysteroid dehydrogenase and 17-20 lyase. Licorice could be considered an adjuvant therapy of hirsutism and polycystic ovary syndrome.


Liquorice in moderate doses primarily affects the cortisol metabolism and only marginally the androgen hormones. Gender may influence the action of liquorice.


The increase in Q was prominent (p<0.0001) and correlated to the rise in BP (p=0.02). The rise in BP was not dependant on age, the change in plasma renin activity or weight. We conclude that patients with essential HT are more sensitive to the inhibition of 11 beta-HSD by liquorice than NT subjects, and that this inhibition causes more clinical symptoms in women than in men.


We twice attempted to replicate this effect of liquorice but could not. We identified differences between our methods and those of the previous study and possible statistical anomalies (including inappropriate use of statistical tests) in the earlier report.



  • Licorice for the Overall Systems

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