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What are MSM's other names?

• Methylsulfonylmethane

What is MSM's recommended dosage?

• Recommended daily intake: 3 g

What supplements interact with MSM?

What can MSM help with?

MSM for Exercise-induced Fatigue

1 study Moderately Positive These results suggest that chronic daily oral supplementation of MSM has alleviating effects on known markers of oxidative stress following acute bouts of exercise in healthy young men.

MSM for Allergy

1 study Slightly Positive The results of this study suggest that MSM supplementation of 2,600 mg/day for 30 days may be efficacious in the reduction of symptoms associated with SAR. Furthermore, few side effects are associated with the use of this compound. Recent acute and subacute chronic toxicologic data on the same source of MSM as used in this study, further validate the safety of this product.

MSM for Muscle Soreness

1 study Slightly Positive It seems that 10-day supplementation with MSM has allowed to decrease muscle damage via effect on antioxidant capacity.

MSM for Osteoarthritis

1 study Slightly Positive Patients with OA of the knee taking MSM for 12 weeks showed an improvement in pain and physical function. These improvements, however, are small and it is yet to be determined if they are of clinical significance.

MSM for Oxidative Damage

2 studies Slightly Positive It seems that 10-day supplementation with MSM has allowed to decrease muscle damage via effect on antioxidant capacity. Slightly Positive MSM, especially when provided at 3.0 grams per day, may favorably influence selected markers of exercise recovery. More work is needed to extend these findings, in particular using a larger sample of subjects and the inclusion of additional markers of exercise recovery and performance.

MSM for Sinusitis

1 study Slightly Positive The results of this study suggest that MSM supplementation of 2,600 mg/day for 30 days may be efficacious in the reduction of symptoms associated with SAR. Furthermore, few side effects are associated with the use of this compound. Recent acute and subacute chronic toxicologic data on the same source of MSM as used in this study, further validate the safety of this product.

MSM for Edema

1 study Slightly Negative The circumference of calf, ankle and foot for both legs were found to decline significantly after 2 weeks of application of the lotion/ but not placebo, and total antioxidant capacity (FRAP) and lipid peroxidation products (MDA), assayed in blood, showed decline in oxidative stress. Application of MSM alone increased the swelling. Thus EDTA+MSM offers an efficacious treatment for lower extremity pitting edema, through reduction in oxidative stress.

What is MSM used for?

What are MSM's effects on the body?