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What are Saffron's other names?

• Crocus sativus

What is Saffron's recommended dosage?

• Recommended daily intake: 30 mg
• Recommended daily doses: 2

What supplements interact with Saffron?

What can Saffron help with?

Saffron for Depression

9 studies Moderately Positive At 6 weeks, Crocus sativus produced a significantly better outcome on the Hamilton depression rating scale than the placebo (d.f. = 1, F = 18.89, p < 0.001). There were no significant differences in the two groups in terms of the observed side effects. The results of this study indicate the efficacy of Crocus sativus in the treatment of mild to moderate depression. A large-scale trial is justified. Moderately Positive At the end of trial, petal of C. sativus was found to be effective similar to fluoxetine in the treatment of mild to moderate depression (F=0.03, d.f.=1, P=0.84). In addition, in the both treatments, the remission rate was 25%. There were no significant differences in the two groups in terms of observed side effects. The present study is supportive of other studies which show antidepressant effect of C. sativus. Moderately Positive Findings from clinical trials conducted to date indicate that saffron supplementation can improve symptoms of depression in adults with MDD. Larger clinical trials, conducted by research teams outside of Iran, with long-term follow-ups are needed before firm conclusions can be made regarding saffron's efficacy and safety for treating depressive symptoms. Moderately Positive It seems saffron may safely and effectively improve some of the fluoxetine-induced sexual problems including arousal, lubrication, and pain. Moderately Positive Saffron at this dose was found to be effective similar to fluoxetine in the treatment of mild to moderate depression (F = 0.13, d.f. = 1, P = 0.71). There were no significant differences in the two groups in terms of observed side effects. The results of this study indicate the efficacy of Crocus sativus in the treatment of mild to moderate depression. A large-scale trial is justified. Moderately Positive Saffron is a tolerable and efficacious treatment for fluoxetine-related erectile dysfunction. Moderately Positive The main overall finding from this study is that saffron may be of therapeutic benefit in the treatment of mild to moderate depression. To the best of our knowledge this is the first clinical trial that supports this indication for saffron. A large-scale trial with placebo control is warranted. Moderately Positive The results of this study indicate the efficacy of C. sativus L. in the treatment of PMS. However, a tolerable adverse effects profile of saffron may well confirm the application of saffron as an alternative treatment for PMS. These results deserved further investigations. Moderately Positive The results of this study indicate the efficacy of petal of C. sativus in the treatment of mild-to-moderate depression. A large-scale trial is justified.

Saffron for Premenstrual Syndrome

1 study Moderately Positive The results of this study indicate the efficacy of C. sativus L. in the treatment of PMS. However, a tolerable adverse effects profile of saffron may well confirm the application of saffron as an alternative treatment for PMS. These results deserved further investigations.

Saffron for Alzheimer's Disease

2 studies Slightly Positive This double-blind, placebo-controlled study suggests that at least in the short-term, saffron is both safe and effective in mild to moderate AD. Larger confirmatory randomized controlled trials are called for. Slightly Positive This phase II study provides preliminary evidence of a possible therapeutic effect of saffron extract in the treatment of patients with mild-to-moderate Alzheimer's disease. This trial is registered with the Iranian Clinical Trials Registry (IRCT138711051556N1).

Saffron for Anxiety

1 study Slightly Positive The present findings support the existence of physiological and psychological effects of saffron odor in women. Our results indicate that saffron odor exert some effects in the treatment of PMS, dysmenorrhea and irregular menstruation. This is the first report to suggest that saffron odor may be effective in treating menstrual distress.

Saffron for Atherosclerosis

1 study Slightly Positive 50 mg of Saffron dissolved in 100 ml of milk was administered twice a day to 20 human subjects. Lipoprotein oxidation susceptibility (LOS) was estimated initially and after 3 and 6 weeks. There was a constant decrease in LOS during this period. From a mean of 66.4 +/- 3.18 it decreased to 38.3 +/- 2.8 in 10 healthy individuals and from 76.0 +/- 3.72 to 48.8 +/- 3.0 in 10 patients of CAD. The significant fall (P < 0.001) in LOS indicates the potential of Saffron as an antioxidant.

What is Saffron used for?

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