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What are Vitamin C's other names?

• 2-oxo-L-threo-hexono-1
• 3-enediol
• 4-lactone-2
• Ascorbate
• Ascorbic Acid
• L-ascorbic acid

What is Vitamin C's recommended dosage?

• Recommended daily intake: 100 - 200 mg

What supplements interact with Vitamin C?

Vitamin C and Iron

1 synergy Increase of Absorption

Vitamin C and Zinc

1 synergy Increase of Absorption

Vitamin C and Aloe vera

1 synergy Increase of Bioavailability

Vitamin C and Green Tea Extract

1 synergy Increase of Antioxidant Potential

Vitamin C and Melatonin

1 synergy Increase of Antioxidant Potential

Vitamin C and Vitamin E

1 synergy Increase of Antioxidant Potential

Vitamin C and Vitamin K

1 synergy Decrease of Cancer Mortality

What can Vitamin C help with?

Vitamin C for Fatigue

1 study Slightly Positive These data provide preliminary evidence that vitamin C status may influence fatigue, heart rate, and perceptions of exertion during moderate exercise in obese individuals.

Vitamin C for Muscle Soreness

4 studies Slightly Positive Glutathione ratio (oxidized glutathione/total glutathione) was significantly increased at 4 and 24 h with P but VC prevented this change. These data suggest that vitamin C pretreatment can reduce MS, delay CK increase, and prevent blood glutathione oxidation with little influence on muscle function loss. Slightly Positive Nevertheless, downhill running provoked a similar increase in circulating markers of muscle damage (creatine kinase activity and myoglobin concentration) and muscle soreness in P and VC groups. Similarly, although downhill running increased plasma interleukin-6, there was no effect from VC supplementation. These results suggest that vitamin C supplementation does not affect interleukin-6 concentrations following eccentric exercise that has a low metabolic component. Slightly Positive The complete lack of any effect on the physiologic and biochemical outcome measures used raises questions about the validity of using oral antioxidant supplementation as a redox modulator of muscle and redox status in healthy humans. Slightly Positive VC supplementation prevented endurance exercise-induced lipid peroxidation and muscle damage but had no effect on inflammatory markers.

Vitamin C for Oxidative Damage

7 studies Slightly Positive Data analysis was carried out using Mann-Whitney U test with p < 0.05 being significant by SPSS software version 16.The result of the study showed a significantly decrease in fasting (p = 0.006) and postprandial MDA (p < 0.001) in vitamin C group compare to placebo group but not in lipid profile. This study suggests that vitamin C supplementation can decrease fasting and postprandial oxidative stress and may prevent diabetes complication. Slightly Positive In conclusion, acute supplementation with a high dose of VC has little or no effect on the hormonal, interleukin-6, or immune response to prolonged exercise and combined ingestion of VC with CHO provides no additional effects compared with CHO alone. Slightly Positive In contrast, vitamin C supplementation decreased urinary concentrations of DHN-MA (three-way interaction p=0.0304) in nonsmoking men compared with nonsmoking women (p<0.05), as well as in nonsmoking men compared with smoking men (p<0.05). Vitamin C supplementation also decreased (p=0.0092) urinary total of metabolites by ~20%. Thus, HPNE metabolites can be reduced favorably in response to improved plasma ascorbic acid concentrations, an effect due to ascorbic acid antioxidant function. Slightly Positive Oral supplementation of vitamin C is not associated with changes in markers of oxidation or endothelial activation in healthy male smokers. Slightly Positive These findings are the first to suggest that oral vitamin C supplementation provides an effective prophylaxis against exercise-induced free radical-mediated lipid peroxidation in human diabetic blood. Slightly Positive These findings suggest that administration of 1,000 mg of ascorbic acid plus 400 IU of alpha-tocopherol for 6 months is not useful for diminishing oxidative stress and DNA damage in healthy elderly adults. Slightly Positive Uric acid and TAC were decreased in group I on all measurement days. However, we did not observe any differences in the clinical status of patients receiving vitamin C during the first ten days of stroke or after 3 months. Although administration of vitamin C (500 mg/day, iv) to ischemic stroke patients since the first day ischemic stroke resulted in elevated serum levels of antioxidants, it did not substantially improve the clinical and functional status of patients after 3 months.

Vitamin C for Vaginitis

1 study Slightly Positive Cure rate in PP was 86.0% with Vit. C (n=50) and 6.1% with placebo (n=49), between-group difference was 79.9% (p < 0.0001). Both Vit. C and placebo were well tolerated and no differences in safety profile were evident between groups. The results support an effective and safe use of silicon-coated Vit. C vaginal tablets in the management of BV.

What is Vitamin C used for?

What are Vitamin C's effects on the body?