Oral intake of proanthocyanidin-rich extract from grape seeds improves chloasma.
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Link to full study
http://www.ncbi.nlm.nih.gov/pubmed/15597304
Conclusion of this study
The beneficial effects of GSE was maximally achieved after 6 months and these was no further improvement after this period. The latter GSE intake for 5 months may prevent chloasma from becoming worse prior to the summer season. GSE is safe and useful for improving chloasma.
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