Upregulation of p53 expression in patients with colorectal cancer by administration of curcumin. – Cost Effective Supplements

Upregulation of p53 expression in patients with colorectal cancer by administration of curcumin.

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Link to full study

http://www.ncbi.nlm.nih.gov/pubmed/21314329

Conclusion of this study

The results showed that curcumin administration increased body weight, decreased serum TNF-alpha levels, increased apoptotic tumor cells, enhanced expression of p53 molecule in tumor tissue, and modulated tumor cell apoptotic pathway. We conclude that the curcumin treatment improves the general health of patients with colorectal cancer via the mechanism of increased p53 molecule expression in tumor cells and consequently speeds up tumor cell apoptosis.