Zinc monotherapy increases serum brain-derived neurotrophic factor (BDNF) levels and decreases depressive symptoms in overweight or obese subjects: a double-blind, randomized, placebo-controlled trial.
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Link to full study
http://www.ncbi.nlm.nih.gov/pubmed/24621065
Conclusion of this study
Zinc monotherapy improves mood in overweight or obese subjects most likely through increasing BDNF levels.
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