Egger's weighted regression statistic suggested low likelihood of publication bias in all analysis (P>0.05 for all), except for the effect on diastolic blood pressure (P=0.046). Based on the currently available literature, grape seed extract appears to significantly lower systolic blood pressure and heart rate, with no effect on lipid or CRP levels. Larger randomized, double-blinded trials evaluating different dosages of grape seed extract and for longer follow-up durations are needed.

Grape Seed Extract

Health conditions analyzed in this study

Functions related to this study

Heart health

1 supplement Slightly Positive Grape Seed Extract

---

Body systems related to this study

Cardiovascular System

1 supplement Grape Seed Extract