Myo-inositol has no beneficial effect on premenstrual dysphoric disorder.
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Link to full study
http://www.ncbi.nlm.nih.gov/pubmed/12478879
Conclusion of this study
Eleven female patients with PMDD diagnosed according to DSM-IV participated in a cross-over, double-blind, placebo-controlled trial. The active drug was myo-inositol, 12 g daily, whereas placebo was d-glucose administered at the same dose. Each drug was given during the luteal phase only (14 days prior to menses). For each patient treatment alternated between these two drugs for six menstrual cycles. No beneficial effect was demonstrated for inositol over placebo.
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