It was found that DHEA administration increased cortisol at several hours during the day. In the treatment group, cortisol was positively associated with cognition at study completion. An increase in negative associations between DHEA(S) levels and cognition was found at completion. Increased cortisol does not explain the cognitive deficits associated with DHEA, suggesting a direct negative effect of exogenous DHEA on cognition.

DHEA

Health conditions analyzed in this study

Functions related to this study

Overall health

1 supplement Slightly Positive DHEA

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Body systems related to this study

Endocrine System

1 supplement DHEA