Crocus sativus L. in the treatment of mild to moderate depression: a double-blind, randomized and placebo-controlled trial. – Cost Effective Supplements

Crocus sativus L. in the treatment of mild to moderate depression: a double-blind, randomized and placebo-controlled trial.

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Link to full study

http://www.ncbi.nlm.nih.gov/pubmed/15852492

Conclusion of this study

At 6 weeks, Crocus sativus produced a significantly better outcome on the Hamilton depression rating scale than the placebo (d.f. = 1, F = 18.89, p < 0.001). There were no significant differences in the two groups in terms of the observed side effects. The results of this study indicate the efficacy of Crocus sativus in the treatment of mild to moderate depression. A large-scale trial is justified.