Can I take Ashwagandha, Myo Inositol and Berberine Together?


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Can I take Ashwagandha and Berberine together?

It is not recommended to take ashwagandha and berberine together because: 

  • Ashwagandha may interact with blood thinner: Both ashwagandha and berberine are found to increase the clotting time, taking both of them together may potentiate the blood-thinning effect, which may prove fatal. 
  • Blood glucose levels: Both of the above supplements lower blood sugar levels, berberine especially has a strong effect on blood glucose-lowering effect, if taken together it may cause hypoglycemia. Ashwagandha is not to be taken with other diabetic medications. 
  • Blood pressure: Berberine lowers blood pressure and is used in the treatment of hypertension. Ashwagandha is also known to reduce blood pressure. Taking both of these supplements together may result in hypotension. 

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Can I take Berberine and Myo-inositol together?

It is not recommended to take berberine and myo-inositol together due to the following effects:

  • Effect on blood sugar level: Both of the supplements lower blood sugar levels, taking them together at an unproven dosage may decrease the blood glucose level below the optimum levels resulting in hypoglycemia. 
  • Effect on blood pressure: A review of articles shows that myo-inositol significantly decreased both systolic and diastolic blood pressure. Berberine produces a similar lowering effect on blood pressure. Consuming both of them together may potentiate the blood pressure-lowering effect and may cause hypotension. 

Can you take Berberine, Quercetin, and Gynostemma together?

Taking Berberine, Quercetin, and Gynostemma at the same time may cause side effects. The following should be considered while using combinations of berberine, quercetin, and gynostemma.

  • Berberine and Quercetin: since both of these supplements decrease blood pressure, special precautions should be taken while consuming. Taking both of the supplements together may lower the blood pressure below safety and can cause hypotension. 
  • Berberine and Gynostemma: Both berberine and gynostemma are known to prolong blood clotting time, consuming both of these together can further increase the blood clotting time which may be fetal. 
  • Gynostemma and Quercetin: There appears to be no interaction between gynostemma and quercetin.
  • Berberine, Quercetin, and Gynostemma: Taking all these three at the same time may result in interaction and adverse effects such as hypotension and bleeding. 

Can you take Chromium and Berberine together?

Chromium and berberine can be taken together because their combination can help to decrease blood glucose levels. 

A study was performed including both chromium and berberine with other ingredients. The study revealed that the combination significantly decreased the levels of glucose, cholesterol, and triglycerides in the patients during the 3-month trial. 

There are a few marketed supplements available that contain chromium and berberine together. However, one should physician with regards to the dosage, because consuming a higher dose may decrease the level of blood sugar below the desired level and cause hypoglycemia.

Can you take Chromium, Berberine, Magnesium, and Resveratrol together?

Chromium, berberine, magnesium, and resveratrol can be taken together to lower blood sugar levels, as all of the mentioned supplements help manage diabetes. They act through various mechanisms to decrease blood glucose levels, increase insulin sensitivity,  increase glucose utilization and decrease intestinal absorption of glucose.

However, only clinically validated products should be used. Consuming unproven combinations of supplements, or taking them individually at the same time may cause adverse reactions. 

Users should consult a physician before consuming these supplements in combination, because the cumulative effect of all these supplements together may cause hypoglycemia.  

Can you take Berberine and NAC together?

It is not advised to take berberine and NAC (N-acetylcysteine) together due to the following:

  • Blood clotting time: NAC may interact with medications or supplements which prolong blood clotting time. Since berberine is known to increase the blood clotting time, NAC may enhance the effect resulting in an increased risk of bruising and bleeding. 
  • Blood sugar levels: Both NAC and berberine decrease blood glucose levels and are used in treating diabetes. Taking both of them together may cause blood glucose levels to unsafe levels. 

Although both of these are supplements and safe for consumption individually, one should consult a physician before taking any combination of supplements. 

Is it safe to take Berberine, Oregano, and Neem together?

Taking berberine, oregano, and neem together may not be safe for the consumer because of the following reasons:

  • Blood clotting time: Both oregano and neem can prolong the blood clotting time. Taking neem and oregano along with berberine can further increase the time required for blood to clot. It can expose the consumer to bleeding and easy bruising. Also, the increased blood clotting time may be fatal in case of surgery or cuts. 
  • Blood sugar levels: Oregano and Neem can interact with medications or supplements which reduce blood glucose levels. Since berberine is known to decrease the blood sugar level, taking all three together may cause hypoglycemia. 

A few online blogs suggest taking berberine, oregano, and neem together for the treatment of SIBO (Small intestinal bacterial overgrowth). Berberine decreases symptoms of SIBO, the antifungal and antibacterial properties of neem decrease the bacteria, and oregano is supposed to enhance the effect of the former two. However, clinical trials and studies are required to substantiate the claim. 

Can I take Gymnema Sylvestre and Berberine together?

A clinically proven combination of gymnema sylvestre and berberine can be taken together to lower blood sugar levels. A few marketed preparations containing both of these ingredients in tablet form are commercially available. However, the dosage of each ingredient should be carefully considered before consumption to avoid adverse reactions. 

Both gymnema sylvestre and berberine are known to decrease blood glucose levels. A 0.5 mg/ day dose of berberine and a 200 mg/ day dose of gymnema sylvestre were able to decrease the levels of blood glucose significantly. Taking both of them together at a higher dosage may result in lowering blood glucose levels than expected, which could result in hypoglycemia and weakness. 

Can I take Berberine and DIM together?

Berberine and DIM (Diindolylmethane) can be taken together since there is no possible interaction and adverse reactions reported for taking both together. Berberine decreases blood glucose levels, and blood pressure helps lose weight, and decreases levels of cholesterol, triglycerides, and fats in the body. 

DIM helps maintain hormonal balance in the body by removing excess estrogen, although the research is very limited. 

There is no marketed preparation for the combination of berberine and DIM, also clinical data regarding safety and dosage is lacking. 

Consult your physician prior to consuming berberine and DIM together. 

Does Berberine interact with thyroid medication?

There are no reports of berberine interacting with thyroid medications. However, the dosage of berberine must be increased if patients are consuming thyroid medication, because of the following:

  • Blood clotting time: Thyroid medications may decrease clotting time, while berberine increases clotting time. Given that both of the supplements work to produce the opposite effect, a higher dosage might be required to achieve the desired result. 
  • Blood glucose levels: Berberine decreases blood glucose levels, while thyroid medications increase blood glucose levels.

The dosage of both medications should be tailored and adjusted for the desired effect. Consult a physician before consuming berberine supplements if you are taking thyroid medications.

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This article makes use of information from the U.S. National Library of Medicine under the terms of the Creative Commons Attribution 4.0 International License.

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Can I take Ashwagandha, Myo Inositol and Berberine Together?
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