Table of Contents
- What are the benefits of Bifidobacterium Breve?
- What is Bifidobacterium Breve?
- What are the health benefits of Bifidobacterium Breve BR03?
- Why is Bifidobacterium Breve strain A1 good for preventing Alzheimer’s disease?
- Is Bifidobacterium Breve B3 Supplement good for weight management?
- What are the side effects of Bifidobacterium Breve?
- What’s Bifidobacterium Breve gram stain?
- Why is Bifidobacterium Breve M16V good for infant health?
- Want to know more?
What are the benefits of Bifidobacterium Breve?
The benefits of Bifidobacterium Breve include the following:
- Boosting the immunity
- Improving digestive health (constipation and diarrhea)
- Enhances the bioavailability of some minerals
- Reduces the risk of gastrointestinal infections
- Prevents eczema (an inflammatory skin condition) in children
- Decreases the risk of colon cancer
- Improves the skin
- Reduces inflammation
Moreover, a study in 2018, revealed that Bifidobacterium Breve plays a role in reducing body fat in people who are about to be obese. Additionally, another review study documents its protective and therapeutic effects in many pediatric diseases.
What is Bifidobacterium Breve?
Bifidobacterium Breve is classified as a probiotic (good bacteria). It’s generally found in the gut, the vagina, as well as from breast milk which explains why breastfed babies are stronger and have better immunity than those who aren’t breastfed.
Aside from its well-known health benefits, Bifidobacterium Breve can also help with the following:
- Breaking down food
- Nutrients absorption
- Fighting infections
- Improving memory and cognitive functions
Nevertheless, more scientific evidence is needed on a larger scale to back up these claims.
In the video below, Dr. Ryan Bentley explains how Bifidobacterium Breve helps decrease diarrhea, constipation, inflammation, asthma, allergies, and eczema:
Recommended Probiotic Supplement with Bifidobacterium Breve:
Biotics 8 has the perfect combination of probiotics, prebiotics, digestive enzymes, fiber, and vitamin D to help support overall gut health and well-being.
What are the health benefits of Bifidobacterium Breve BR03?
The health benefits of Bifidobacterium Breve BR03 include the following:
- Reducing inflammation (anti-inflammatory properties)
- Eliminating infections (antipathogenic properties)
- Managing upset stomach (especially constipation)
- Regulating weight
- Treating several conditions in the urogenital system (like cystitis and kidney stones)
Evidently, a study in 2014 and another one in 2016, prove the significant positive impact of Bifidobacterium Breve BR03 in treating children with fecal coliforms and their recommended use in everyday clinical practice.
Recently, a study in 2021 show the beneficial effect of Bifidobacterium Breve BR03 on treating insulin sensitivity in obese individuals which makes it a promising therapeutic option pending further studies.
Why is Bifidobacterium Breve strain A1 good for preventing Alzheimer’s disease?
Bifidobacterium Breve strain A1 is good for preventing Alzheimer’s disease as it can interfere with the disease pathways and suppress the expression of specific proteins that lead to cognitive impairment.
In fact, a study in 2020 deemed Bifidobacterium Breve strain A1 both safe and beneficial in treating cognitively impaired older adults.
Is the Bifidobacterium Breve B3 Supplement good for weight management?
The Bifidobacterium Breve B3 supplement is good for weight management by preventing body fat build-up in a modulatory way and improving the function of the intestinal barrier resulting in a more controlled inflammatory reaction and manageable metabolic function.
A study in 2015 concluded that Bifidobacterium Breve B3 oral supplement administration had beneficial potential in treating metabolic disorders and obesity.
What are the side effects of Bifidobacterium Breve?
The side effects of Bifidobacterium Breve include the following:
- Upset stomach
- Can increase the risk of infections in some people who have other underlying conditions (immuno-compromised or suffering from a digestive disorder)
So far, Bifidobacterium Breve is labeled safe but as a 2019 study pointed out, there’s still a great need for further investigations to determine the long-term safety and efficacy of these probiotics.
What’s Bifidobacterium Breve gram stain?
Bifidobacterium Breve gram stain is the way it looks under a microscope. It’s a gram-positive bacterium that stains cells irregularly. Nevertheless, characteristic appearance can differ from sample to sample according to each case and bacterium strain.
Why is Bifidobacterium Breve M16V good for infant health?
Bifidobacterium Breve M 16V is good for infant health as it supports healthy growth and well-being through the following functions:
- Promoting respiratory health
- Supporting skin health
- Boosting a healthy immune system
- Reducing inflammation
- Protection against infections
- Increasing levels of bifidobacteria (good bacteria)
A study in 2016 revealed that B. Breve M 16V reduced the risk of necrotizing enterocolitis (NEC) in preterm neonates. Another study in 2021, showed that when mothers take B. Breve M 16V, they alleviate inflammatory symptoms caused by air pollution in their newborns.
Moreover, B. Breve M 16V also showed improvements in the gut microbiota of several infants.
Want to know more?
Click the links below to access the individual topic pages:
This article makes use of information from the U.S. National Library of Medicine under the terms of the Creative Commons Attribution 4.0 International License.
- Minami J, Iwabuchi N, Tanaka M, Yamauchi K, Xiao JZ, Abe F, Sakane N. Effects of Bifidobacterium breve B-3 on body fat reductions in pre-obese adults: a randomized, double-blind, placebo-controlled trial. Biosci Microbiota Food Health. 2018;37(3):67-75. DOI: 10.12938/bmfh.18-001. Epub 2018 May 8. PMID: 30094122; PMCID: PMC6081611.
- Bozzi Cionci N, Baffoni L, Gaggìa F, Di Gioia D. Therapeutic Microbiology: The Role of Bifidobacterium breve as Food Supplement for the Prevention/Treatment of Paediatric Diseases. Nutrients. 2018 Nov 10;10(11):1723. DOI: 10.3390/nu10111723. PMID: 30423810; PMCID: PMC6265827.
- Dore MP, Bibbò S, Fresi G, Bassotti G, Pes GM. Side Effects Associated with Probiotic Use in Adult Patients with Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Nutrients. 2019 Dec 2;11(12):2913. DOI: 10.3390/nu11122913. PMID: 31810233; PMCID: PMC6950558.
- Mogna L, Del Piano M, Mogna G. Capability of the two microorganisms Bifidobacterium breve B632 and Bifidobacterium breve BR03 to colonize the intestinal microbiota of children. J Clin Gastroenterol. 2014 Nov-Dec;48 Suppl 1:S37-9. DOI: 10.1097/MCG.0000000000000234. PMID: 25291125.
- Giglione, Enza MD*; Prodam, Flavia PhD*; Bellone, Simonetta PhD*; Monticone, Sonia MD*; Beux, Sheila BS*; Marolda, Agostina MD*; Pagani, Alessia MD*; Di Gioia, Diana PhD†; Del Piano, Mario MD‡; Mogna, Giovanni BS§; Bona, Gianni MD* The Association of Bifidobacterium breve BR03 and B632 is Effective to Prevent Colics in Bottle-fed Infants, Journal of Clinical Gastroenterology: November/December 2016 – Volume 50 – Issue – p S164-S167 DOI: 10.1097/MCG.0000000000000693
- Solito A, Bozzi Cionci N, Calgaro M, Caputo M, Vannini L, Hasballa I, Archero F, Giglione E, Ricotti R, Walker GE, Petri A, Agosti E, Bellomo G, Aimaretti G, Bona G, Bellone S, Amoruso A, Pane M, Di Gioia D, Vitulo N, Prodam F. Supplementation with Bifidobacterium breve BR03 and B632 strains improved insulin sensitivity in children and adolescents with obesity in a cross-over, randomized double-blind placebo-controlled trial. Clin Nutr. 2021 Jul;40(7):4585-4594. DOI: 10.1016/j.clnu.2021.06.002. Epub 2021 Jun 11. PMID: 34229263.
- Minami J, Kondo S, Yanagisawa N, Odamaki T, Xiao JZ, Abe F, Nakajima S, Hamamoto Y, Saitoh S, Shimoda T. Oral administration of Bifidobacterium breve B-3 modifies metabolic functions in adults with obese tendencies in a randomised controlled trial. J Nutr Sci. 2015 May 4;4:e17. doi: 10.1017/jns.2015.5. PMID: 26090097; PMCID: PMC4463018.
- Kobayashi, Y., Sugahara, H., Shimada, K. et al. Therapeutic potential of Bifidobacterium breve strain A1 for preventing cognitive impairment in Alzheimer’s disease. Sci Rep 7, 13510 (2017). https://doi.org/10.1038/s41598-017-13368-2
- Xiao J, Katsumata N, Bernier F, Ohno K, Yamauchi Y, Odamaki T, Yoshikawa K, Ito K, Kaneko T. Probiotic Bifidobacterium breve in Improving Cognitive Functions of Older Adults with Suspected Mild Cognitive Impairment: A Randomized, Double-Blind, Placebo-Controlled Trial. J Alzheimers Dis. 2020;77(1):139-147. doi: 10.3233/JAD-200488. PMID: 32623402; PMCID: PMC7592675.
- Butta H, Sardana R, Vaishya R, Singh KN, Mendiratta L. Bifidobacterium: An Emerging Clinically Significant Metronidazole-resistant Anaerobe of Mixed Pyogenic Infections. Cureus. 2017 Apr 4;9(4):e1134. DOI: 10.7759/cureus.1134. PMID: 28480152; PMCID: PMC5418030.
- Wong CB, Iwabuchi N, Xiao JZ. Exploring the Science behind Bifidobacterium breve M-16V in Infant Health. Nutrients. 2019 Jul 25;11(8):1724. DOI: 10.3390/nu11081724. PMID: 31349739; PMCID: PMC6723912.
- Patole SK, Rao SC, Keil AD, Nathan EA, Doherty DA, Simmer KN. Benefits of Bifidobacterium breve M-16V Supplementation in Preterm Neonates – A Retrospective Cohort Study. PLoS One. 2016 Mar 8;11(3):e0150775. DOI: 10.1371/journal.pone.0150775. PMID: 26953798; PMCID: PMC4783036.
- Terada-Ikeda C, Kitabatake M, Hiraku A, Kato K, Yasui S, Imakita N, Ouji-Sageshima N, Iwabuchi N, Hamada K, Ito T. Maternal supplementation with Bifidobacterium breve M-16V prevents their offspring from allergic airway inflammation accelerated by the prenatal exposure to an air pollutant aerosol. PLoS One. 2020 Sep 11;15(9):e0238923. DOI: 10.1371/journal.pone.0238923. PMID: 32915886; PMCID: PMC7485856.
- Horigome A, Hisata K, Odamaki T, Iwabuchi N, Xiao JZ, Shimizu T. Colonization of Supplemented Bifidobacterium breve M-16V in Low Birth Weight Infants and Its Effects on Their Gut Microbiota Weeks Post-administration. Front Microbiol. 2021 Apr 7;12:610080. DOI: 10.3389/fmicb.2021.610080. PMID: 33897631; PMCID: PMC8058467.